There is evidence that the peoples of Karmah had developed an advanced civilization as early as 8000 B.C.E. The area farmed grain, produced pottery, and traded gold, ivory, and copper, serving as a important stop on trade routes between Egypt and the rest of the world.
At the beginning of the third millennium, between 3000 and 2400 B.C., a culture known as Pre-Karmah developed between the second and the fourth cataract but these populations must abandon their villages at the rhythm of progression of aridity in order to set closer to the Nile.
Egypt and Karmah battled over control of Lower Nubia (southern Egypt) from 1570 B.C.E. to 1450 B.C.E., ending with the Egyptians taking control of the capital. Amenhotep I conquered Karmah destroying the kingdom of Cush, Nubia was colonized. At this time the Nubians became assimilated into Egyptian culture.
Karmah kingdom of Nubia